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AVN-944

Product Specifications

CAS Number

297730-17-7

Synonyms

VX-944

SKU

C04221-1mg

Additionnal Information

AVN-944 (VX-944) is an orally active, potent, selective, noncompetitive and specific inhibitor of IMPDH (inosine monophosphate dehydrogenase) . AVN-944 is an essential rate-limiting enzyme in de novo guanine nucleotide synthesis. AVN-944 is also an inhibitor of arenavirus RNA synthesis, and blocks arenavirus infection. AVN-944 has broad anti-cancer activities, and can be used for multiple myeloma (MM) and acute myeloid leukemia (AML) research.

Storage Conditions

3 years-20°C powder 2 years-80°C in solvent

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