Nolatrexed dihydrochloride
Product Specifications
CAS Number
152946-68-4
Synonyms
AG 337
SKU
C04019-5mg
Additionnal Information
Nolatrexed dihydrochloride (AG 337) is a non-competitive lipophilic inhibitor of thymidylate synthase, interacts at the folate cofactor binding site of the enzyme, with a Ki of 11 nM for human thymidylate synthase. Nolatrexed dihydrochloride (AG 337) induces cell cycle arrest in S phase of cancer cells. Anti-cancer activity.
Storage Conditions
3 years-20°C powder 2 years-80°C in solvent
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