Saclofen
Product Specifications
CAS Number
125464-42-8
SKU
C03931-5mg
Additionnal Information
Saclofen is an orally available competitive GABAB receptor antagonist with an IC50 of 7.8 μM, but it has a weaker antagonistic effect on GABAB1b and GABAB2 heterodimer recombinant receptors. Saclofen can inhibit the binding of baclofen (HY-B007) to rat cerebellar membranes and block the phase shifts in circadian rhythms caused by baclofen. Saclofen has also shown anti-inflammatory and analgesic effects in rats.
Storage Conditions
3 years-20°C powder 2 years-80°C in solvent
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