Olverembatinib
Product Specifications
CAS Number
1257628-77-5
Synonyms
GZD824, HQP1351
SKU
C03795-5mg
Target
Bcr-Abl
Applications
Protein Tyrosine Kinase
Additionnal Information
Olverembatinib (GZD824, HQP1351) is an orally bioavailable inhibitor of pan-Bcr-Abl. It effectively inhibits a wide range of Bcr-Abl mutants, with IC50 of 0.34 nM and 0.68 nM for native Bcr-Abl and the Bcr-AblT315I mutant, respectively. It also induces tumor regression in mouse xenograft models.
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