Cilastatin sodium
Product Specifications
CAS Number
81129-83-1
Synonyms
MK0791 sodium
SKU
C03682-5mg
Target
Others
Applications
Others
Additionnal Information
Cilastatin sodium (MK0791 sodium) is a reversible, competitive inhibitor of renal dehydropeptidase I (also known as membrane dipeptidase, MDP), with an IC50 of 0.1 μM. It is primarily used in combination with imipenem to enhance the antibiotic's effectiveness against a broad spectrum of bacterial infections by preventing its degradation in the kidneys.
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