Bazedoxifene
Product Specifications
CAS Number
198481-32-2
Synonyms
TSE-424
SKU
C03679-5mg
Target
Estrogen/progestogen Receptor
Applications
Endocrinology & Hormones
Additionnal Information
Bazedoxifene (TSE-424) is a selective estrogen receptor modulator that binds to and activates ERα and ERβ with IC50 values of 26 nM and 99 nM, respectively. It also inhibits IL-6/GP130 interactions, suppresses STAT3 signaling, induces apoptosis, and reduces tumor growth, viability, and colony formation in cancer models, while being studied for effects on bone density, uterine health, and CNS vasomotor responses.
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
127375-ML650 100 µL
GLYAT (ACGNAT, CAT, GAT, Glycine N-acyltransferase, Acyl-CoA:glycine N-acyltransferase, Aralkyl acyl-CoA N-acyltransferase, Aralkyl acyl-CoA:amino acid N-acyltransferase, Benzoyl-coenzyme A:glycine N-acyltransferase, Glycine N-benzoyltransferase, HRP-1 (CLP) ) (MaxLight 650)
Ask
View Details 