Osavampator

Product Specifications

CAS Number

1358751-06-0

Synonyms

TAK-653, NBI-1065845

SKU

C03620-5mg

Target

GluR

Applications

Neuronal Signaling

Additionnal Information

Osavampator (TAK-653, NBI-1065845) is a positive allosteric modulator (PAM) of AMPA receptors. It enhances glutamate-induced calcium influx in CHO cells expressing human AMPA receptors with an EC50 of 3.3 μM and potentiates AMPA receptor-mediated currents in rat primary hippocampal neurons with an EC50 of 4.4 μM.