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ATX968

Product Specifications

CAS Number

2973395-71-8

Synonyms

DHX9-IN-2

SKU

C03597-5mg

Target

DNA/RNA Synthesis

Applications

Cell Cycle

Additionnal Information

ATX968 (DHX9-IN-2) is a potent, selective, and orally bioavailable inhibitor of DHX9 helicase with an IC50 of 8 nM. It induces strong and sustained tumor growth inhibition or regression in MSI-H/dMMR colorectal cancer (CRC) xenograft models.

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