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YB-3-17

Product Specifications

CAS Number

2940242-88-4

SKU

C03583-5mg

Target

MTOR

Applications

PI3K/Akt/mTOR

Additionnal Information

YB-3−17 is a dual-target compound that effectively and selectively inhibits mTOR with an IC50 of 0.22 nM, while promoting GSPT1 degradation with an IC50 of 5 nM, leading to substantial tumor growth inhibition both in vitro and in vivo. It also exhibits significant antiproliferative activity in glioblastoma models.

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