Zileuton sodium

Zileuton sodium (A 64077 sodium) is a potent, selective, and specific inhibitor of 5-lipoxygenase, exhibiting inflammatory activities. Zileuton sodium prevents polyp formation efficiently by reducing tumor-associated and systemic inflammation in in vivo models. Zileuton sodium also acts as a potential chemo-preventive agent in patients that are at high risk of developing colon cancer.