Afatinib free base
Product Specifications
CAS Number
439081-18-2
Synonyms
Gilotrif, BIBW2992, Boehringer Ingelheim
SKU
C03374-100mg
Target
EGFR
Applications
Protein Tyrosine Kinase
Additionnal Information
Afatinib free base (Gilotrif, BIBW2992, Boehringer Ingelheim) is a second-generation tyrosine kinase inhibitor (TKI) that irreversibly inhibits EGFR and HER2, with IC50 of 0.5 nM, 0.4 nM, 14 nM and 1 nM for wild-type EGFR, EGFR-L858R, HER2, ErbB4, respectively.
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