What is the catalog number for GSK-J4?

The catalog number for GSK-J4 is C03353.

What sizes are available for GSK-J4?

GSK-J4 is available in the following size(s): 5 mg.

GSK-J4 is currently made to order / not held in immediate stock. Contact us for lead time.

GSK-J4

Product Specifications

CAS Number

1373423-53-0

SKU

C03353-5mg

Target

Histone Demethylase

Applications

Epigenetics

Additionnal Information

GSK-J4 is a potent dual inhibitor of H3K27me3/me2-demethylases JMJD3/KDM6B and UTX/KDM6A that ameliorates experimental autoimmune encephalomyelitis (EAE) . It is also an inhibitor of TNF-α production, with an IC50 of 9 μM. It shows potential as a treatment for inflammatory and autoimmune disorders.