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Adezmapimod hydrochloride

Product Specifications

CAS Number

869185-85-3

Synonyms

RWJ 64809 hydrochloride, SB 203580 hydrochloride

SKU

C03350-5mg

Target

P38 MAPK

Applications

MAPK

Additionnal Information

Adezmapimod hydrochloride (RWJ 64809 hydrochloride, SB 203580 hydrochloride) is an inhibitor of the MAPK family member termed as stress-activated protein kinase 2a (SAPK2a; also known as p38) . It exhibits IC50 of SAPK2a/p38 and SAPK2b/p38β2 with IC50 values of 50 nM and 500 nM respectively and can be used in research of chronic inflammatory diseases, such as rheumatoid arthritis.

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