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Oveporexton (TAK-861)

Product Specifications

CAS Number

2460722-04-5

SKU

C03320-1mg

Target

OX Receptor

Applications

Neuronal Signaling

Additionnal Information

Oveporexton (TAK-861) is a potent, orally bioavailable agonist of orexin receptor 2 (OX2R), with an EC50 of 2.5 nM in calcium mobilization assays. It induces dose-dependent membrane depolarization in histaminergic neurons within the mouse tuberomammillary nucleus (TMN) with an EC50 of 31.7 nM.

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