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COH34

Product Specifications

CAS Number

906439-72-3

SKU

C03317-5mg

Target

PARG

Applications

Metabolism

Additionnal Information

COH34 is a potent and specific inhibitor of poly (ADP-ribose) glycohydrolase (PARG) with an IC50 value of 0.37 nM. It binds to the catalytic domain of PARG with Kd of 0.547 μM thereby prolonging PARylation at DNA lesions and trapping DNA repair factors and can be used in research of cancer therapies.

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