MGD-28
Product Specifications
CAS Number
2991818-13-2
SKU
C03310-5mg
Target
Immunology & Inflammation related
Applications
Immunology & Inflammation
Additionnal Information
MGD-28 is a potent and orally active degrader of Cereblon (CRBN) -dependent IKAROS proteins. It effectively degrades IKZF1 (DC50 = 3.8 nM), IKZF2 (DC50 = 56.3 nM), and IKZF3 (DC50 = 7.1 nM) . It demonstrates significant antiproliferative potency across various hematologic cancer cell lines.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
479198 100 µL
DDX42 (ATP-dependent RNA Helicase DDX42, DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 42)
Sign In for Pricing
View Details 
132550-PE 100 µL
RHEB (GTP-binding Protein Rheb, Ras Homolog Enriched in Brain, RHEB2, MGC111559) (PE)
Sign In for Pricing
View Details