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MGD-28

Product Specifications

CAS Number

2991818-13-2

SKU

C03310-5mg

Target

Immunology & Inflammation related

Applications

Immunology & Inflammation

Additionnal Information

MGD-28 is a potent and orally active degrader of Cereblon (CRBN) -dependent IKAROS proteins. It effectively degrades IKZF1 (DC50 = 3.8 nM), IKZF2 (DC50 = 56.3 nM), and IKZF3 (DC50 = 7.1 nM) . It demonstrates significant antiproliferative potency across various hematologic cancer cell lines.

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