SDU-071

Product Specifications

CAS Number

3036109-10-8

SKU

C03300-5mg

Target

Epigenetic Reader Domain

Applications

Epigenetics

Additionnal Information

SDU-071 is an inhibitor of BRD4-p53 protein-protein interaction with IC50 of 2.7 μM, which suppresses MDA-MB-231 triple-negative breast cancer (TNBC) cell migration, invasion, and in vivo tumor growth. It also exhibits antiproliferative activity in concentration concentration-dependent manner, with IC50 of 10.5 μM (72 h) and 12.6 μM (96 h) in MDA-MB-231 cells.