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RGT-018

Product Specifications

CAS Number

2794934-49-7

SKU

C03288-5mg

Target

Ras

Applications

Apoptosis

Additionnal Information

RGT-018, is a potent and selective inhibitor of SOS1. It blocks the interaction of KRAS:SOS1 with an IC50 of 8 nM and inhibited KRAS signaling and the proliferation of KRAS-driven cancer cells. It may exhibit potent anticancer activity against NSCLC, colorectal cancer, and pancreatic cancer.

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