OPB-171775

Product Specifications

CAS Number

2131210-15-4

SKU

C03287-5mg

Target

PDE

Applications

Metabolism

Additionnal Information

OPB-171775 functions as a molecular glue, promoting the formation of a complex between phosphodiesterase 3A (PDE3A) and Schlafen family member 12 (SLFN12) . This interaction triggers multiple cellular stresses, ultimately leading to cell death. It also demonstrates significant anticancer activity in patient-derived xenograft (PDX) models of Gastrointestinal stromal tumor (GIST) .