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THZ-P1-2

Product Specifications

CAS Number

2058075-45-7

SKU

C03285-5mg

Target

Autophagy

Applications

Autophagy

Additionnal Information

THZ-P1-2 is an inhibitor of PI5P4K, which covalently binds to cysteines on a disordered loop in PI5P4Kα/β/γ. It inhibits PI5P4Kα kinase activity with an IC50 of 190 nM and disrupts autophagy by impairing autophagosome clearance and increasing TFEB nuclear localization.

Available Sizes

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