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ZX703

Product Specifications

SKU

C03259-1mg

Target

Peroxidases

Applications

Metabolism

Additionnal Information

ZX703 is a proteolysis targeting chimera (PROTAC), that is a degrader of GPX4 through the ubiquitin-proteasome and the autophagy-lysosome with a DC50 of 0.315 μM. It induces the accumulation of lipid reactive oxygen species (ROS), thereby inducing ferroptosis cancer cells.

Available Sizes

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