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MIRA-1

Product Specifications

CAS Number

72835-26-8

Synonyms

NSC 19630

SKU

C03245-5mg

Target

Others

Applications

Others

Additionnal Information

MIRA-1 (NSC 19630), a maleimide compound, is a selective inhibitor of Werner syndrome WRN helicase activity with an IC50 of 20 μM while sparing ATPase and exonuclease activities. It reactivates mutant p53, inducing apoptosis in various human solid tumor cell lines with tetracycline-regulated mutant p53.

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