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BHPI

Product Specifications

CAS Number

56632-39-4

SKU

C03235-5mg

Target

Estrogen/progestogen Receptor

Applications

Endocrinology & Hormones

Additionnal Information

BHPI is a potent noncompetitive inhibitor of estrogen receptor α (ERα), which disrupts the protective estrogen–ERα-mediated activation of the unfolded protein response (UPR), leading to sustained UPR activation. It specifically inhibits the growth of drug-resistant ERα-positive breast and ovarian cancer cells and induces significant tumor regression in a mouse xenograft model of breast cancer.

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