Trilaciclib dihydrochloride
Product Specifications
CAS Number
1977495-97-8
Synonyms
G1T28 dihydrochloride
SKU
C03208-5mg
Target
CDK
Applications
Cell Cycle
Additionnal Information
Trilaciclib dihydrochloride (G1T28 dihydrochloride) is a potent inhibitor of CDK4/cyclin D1 and CDK6/cyclin D3 with IC50s of 1 nM and 4 nM for CDK4 and CDK6, respectively. Trilaciclib hydrochloride regulates cell proliferation and protects against chemotherapy toxicity in murine and canine bone marrow cells.
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MED26 (Mediator of RNA Polymerase II Transcription Subunit 26, Activator-recruited Cofactor 70kD Component, ARC70, Cofactor Required for Sp1 Transcriptional Activation Subunit 7, CRSP Complex Subunit 7, Mediator Complex Subunit 26, Transcriptional Coactivator CRSP70, ARC70, CRSP7) (APC)
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