EGFR T790M/L858R-IN-4
EGFR T790M/L858R-IN-4 (Example 14) is a potent EGFRT790M/L858R inhibitor with anticancer effects[1].
Product Specifications
CAS Number
3032760-34-9
UNSPSC
12352005
Target
EGFR
Type
Reference compound
Related Pathways
JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/egfr-t790m-l858r-in-4.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=CC(NC2=NC(N3C=CC4=CC=CN=C43)=CC=N2)=C(OC)C=C1C)/C=C/CN(C)C
Molecular Formula
C25H27N7O2
Molecular Weight
457.53
References & Citations
[1]Guoqing Paul Chen, et al. Novel pyrimidine compound as kinase inhibitors with biological activities on egfr mutants. WO2024064091A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
EGFR/ErbB1/HER1
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