Poseltinib
Product Specifications
CAS Number
1353552-97-2
Synonyms
HM71224, LY3337641
SKU
C02206-5mg
Target
BTK
Applications
Protein Tyrosine Kinase
Smiles
CN1CCN (CC1) C2=CC=C (NC3=NC (=C4OC=CC4=N3) OC5=CC (=CC=C5) NC (=O) C=C) C=C2
Additionnal Information
Poseltinib (HM71224, LY3337641) shows a highly selective inhibition for Bruton’s tyrosine kinase (BTK) with IC50 of 1.95 nM, in which the selectivity toward other BMX, TEC and TXK are 0.3, 2.3 and 2.4 fold, respectively.
Storage Conditions
3 years -20°C powder
Curated Selection
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