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Poseltinib

Product Specifications

CAS Number

1353552-97-2

Synonyms

HM71224, LY3337641

SKU

C02206-5mg

Target

BTK

Applications

Protein Tyrosine Kinase

Smiles

CN1CCN (CC1) C2=CC=C (NC3=NC (=C4OC=CC4=N3) OC5=CC (=CC=C5) NC (=O) C=C) C=C2

Additionnal Information

Poseltinib (HM71224, LY3337641) shows a highly selective inhibition for Bruton’s tyrosine kinase (BTK) with IC50 of 1.95 nM, in which the selectivity toward other BMX, TEC and TXK are 0.3, 2.3 and 2.4 fold, respectively.

Storage Conditions

3 years -20°C powder

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