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Kira8

Product Specifications

CAS Number

1630086-20-2

Synonyms

Ire-1 inhibitor, AMG-18

SKU

C02135-5mg

Target

IRE1

Applications

ER stress & UPR

Smiles

CC1=C (OC2=C (C=CC=N2) C3=NC (=NC=C3) NC4CCCNC4) C5=C (C=C1) C (=CC=C5) N[S; v6] (=O) (=O) C6=C (Cl) C=CC=C6

Additionnal Information

Kira8 (Ire-1 inhibitor, AMG-18) is a mono-selective IRE1α inhibitor that allosterically attenuates IRE1α RNase activity with an IC50 of 5.9 nM.

Storage Conditions

3 years -20°C powder

Available Sizes

Frequently Asked Questions

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