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Doxorubicin

Product Specifications

CAS Number

23214-92-8

Synonyms

Adriamycin, Hydroxydaunorubicin, DOX

SKU

C02104-5mg

Target

Topoisomerase

Applications

DNA Damage/DNA Repair

Smiles

COC1=C2C (=O) C3=C (C (=C4CC (O) (CC (OC5CC (N) C (O) C (C) O5) C4=C3O) C (=O) CO) O) C (=O) C2=CC=C1

Additionnal Information

Adriamycin (Doxorubicin, Hydroxydaunorubicin), a cytotoxic anthracycline antibiotic, is an anti-cancer chemotherapy agent, inhibits topoisomerase II with an IC50 of 2.67 μM, thus stopping DNA replication, and induces apoptosis, also inhibits human DNA topoisomerase I with an IC50 of 0.8 μM.

Storage Conditions

3 years -20°C (in the dark) powder1 year -80°C (in the dark) in solvent

Available Sizes

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