HVEGF-IN-1
Product Specifications
CAS Number
1637443-98-1
SKU
C02077-5mg
Target
VEGFR
Applications
Protein Tyrosine Kinase
Smiles
CCN (CC) CCOC1=CC=C (NC2=NC (=NC3=C2C=CC=C3) C4=C (NC (=O) CCN5CCN (C) CC5) C=CC=C4) C=C1
Additionnal Information
HVEGF-IN-1, a quinazoline derivative, specifically binds to the G-rich sequence in the internal ribosome entry site A (IRES-A) with a Kd of 0.928 μM, therefore destabilizes the G-quadruplex structure, , also hinders tumor cells migration and represses tumor growth by decreasing VEGF-A protein expression.
Storage Conditions
3 years -20°C powder
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