YD23
Product Specifications
CAS Number
2951015-29-3
SKU
C01999-5mg
Target
PROTAC
Applications
Others
Additionnal Information
YD23 is a PROTAC which induces the degradation of SMARCA2. It reduces chromatin accessibility in SMARCA4-deficient cells, affecting gene enhancers related to cell cycle and growth regulation, which leads to the downregulation of several cell cycle genes. It also selectively inhibits the growth of SMARCA4 mutant lung cancer cells in vitro.
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