MS8709
Product Specifications
CAS Number
3060730-06-2
Synonyms
EX-A11295
SKU
C01991-5mg
Target
G9a/GLP
Applications
Epigenetics
Additionnal Information
MS8709 (EX-A11295) is a first-in-class G9a/GLP proteolysis targeting chimera (PROTAC) degrader, that induces G9a/GLP degradation in a concentration, time, and ubiquitin-proteasome system (UPS) -dependent manner, and does not alter the mRNA expression of G9a/GLP over other methyltransferases. It displays superior cell growth inhibition in prostate, leukemia, and lung cancer cells over parent G9a/GLP inhibitors.
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6289248-01 0.1 mL
CSF3R, ID (CSF3R, GCSFR, Granulocyte colony-stimulating factor receptor, CD114) (MaxLight 490)
Ask
View Details 
MBS6289248-02 5x 0.1 mL
CSF3R, ID (CSF3R, GCSFR, Granulocyte colony-stimulating factor receptor, CD114) (MaxLight 490)
Ask
View Details MBS6168251-01 0.1 mL
GCLM (Glutamate-Cysteine Ligase, modifier Subunit, GLCLR) (APC)
Ask
View Details MBS6168251-02 5x 0.1 mL
GCLM (Glutamate-Cysteine Ligase, modifier Subunit, GLCLR) (APC)
Ask
View Details