Tunlametinib
Product Specifications
CAS Number
1801756-06-8
Synonyms
HL-085
SKU
C01969-5mg
Target
MEK
Applications
Protein Tyrosine Kinase
Additionnal Information
Tunlametinib (HL-085) is a highly selective and oral inhibitor of MEK1/2 with an IC50 of 1.9 nM for MEK1, with the potential to treat RAS/RAF mutant cancers. It also induces cell cycle arrest at the G0/G1 phase and promotes apoptosis in a dose-dependent manner. It also exhibits antitumor activity in patients with advanced NRAS-mutant melanoma.
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
253601-ML650 100 µL
ZFYVE19 (Zinc Finger, FYVE Domain Containing 19, FLJ14840, MPFYVE) (MaxLight 650)
Ask
View Details 036719-APC 200 µL
HOXC4, CT (HOXC4, HOX3E, Homeobox protein Hox-C4, Homeobox protein CP19, Homeobox protein Hox-3E) (APC) discontinued
Ask
View Details 
NBP3-28082-100ug 100 µg
CHO Monoclonal CA125/MUC16 Antibody (sofituzumab) - Humanized - (Dry Ice)
Ask
View Details