Tunlametinib
Product Specifications
CAS Number
1801756-06-8
Synonyms
HL-085
SKU
C01969-5mg
Target
MEK
Applications
Protein Tyrosine Kinase
Additionnal Information
Tunlametinib (HL-085) is a highly selective and oral inhibitor of MEK1/2 with an IC50 of 1.9 nM for MEK1, with the potential to treat RAS/RAF mutant cancers. It also induces cell cycle arrest at the G0/G1 phase and promotes apoptosis in a dose-dependent manner. It also exhibits antitumor activity in patients with advanced NRAS-mutant melanoma.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
GTR15319688 1 Vial
Lentiviral human RTN4R shRNA (UAS) - Lentiviral human RTN4R shRNA (UAS) (25)
Sign In for Pricing
View Details 