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TI17

Product Specifications

CAS Number

1005178-02-8

SKU

C01955-5mg

Target

THR

Applications

Endocrinology & Hormones

Additionnal Information

TI17 is an inhibitor of thyroid hormone receptor-interacting protein Trip13. TI17 efficiently suppresses the proliferation of multiple myeloma (MM) cells and triggers cell cycle arrest and apoptosis. Trip13, an AAA-ATPase involved in double-strand break (DSB) repair, is targeted by TI17, leading to impaired function and heightened DNA damage.

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