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DDO-2728

Product Specifications

CAS Number

3029515-97-4

SKU

C01949-5mg

Target

Others

Applications

Others

Additionnal Information

DDO-2728 is a selective pyrazolopyrimidine-based inhibitor of ALKBH5 with an IC50 of 2.97 μM. It increases the levels of N6-methyladenosine (m6A) modifications in acute myeloid leukemia (AML) cells and exhibits antiproliferative activity in these cells. It also demonstrates anti-tumor efficacy in the MV4−11 xenograft model.

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