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Nedometinib

Product Specifications

CAS Number

2252314-46-6

Synonyms

NFX-179

SKU

C01938-5mg

Target

MEK

Applications

Protein Tyrosine Kinase

Additionnal Information

Nedometinib (NFX-179) is a highly specific and potent inhibitor of MEK1 with an IC50 of 135 nM. It also results in suppression of p-ERK levels and can be used in research and treatment of cutaneous neurofibromas (cNFs) associated with neurofibromatosis type 1 (NF1) .

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