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Fulzerasib

Product Specifications

CAS Number

2641747-54-6

Synonyms

IBI351, GFH925

SKU

C01904-1mg

Target

Ras

Applications

Apoptosis

Additionnal Information

Fulzerasib (IBI351, GFH925) is an irreversible small molecule inhibitor for KRAS G12C mutation blocking KRAS pathway signaling pERK with an IC50 of 37 nM. It demonstrates potent anti-tumor activity in multiple KRAS G12C-mutant tumor models including human pancreatic cancer, human lung adenocarcinoma, colorectal adenocarcinoma, and lung cancer models.

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