Lorundrostat
Product Specifications
CAS Number
1820940-17-7
Synonyms
MT-4129
SKU
C01888-5mg
Target
P450 (e.g. CYP17)
Applications
Metabolism
Additionnal Information
Lorundrostat (MT-4129) is a highly selective inhibitor of CYP11B2 (aldosterone synthase), with inhibition constant (Ki) values of 1.27 nM for hCYP11B2 and 475 nM for hCYP11B1. It demonstrates potential as a safe and effective treatment for aldosterone-dependent uncontrolled hypertension, including cases of treatment-resistant hypertension.
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