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N6F11

Product Specifications

CAS Number

851398-76-0

SKU

C01885-50mg

Target

Ferroptosis

Applications

Apoptosis

Additionnal Information

N6F11 is an inducer of ferroptosis. N6F11 is bound to the RING domain of the E3 ubiquitin ligase tripartite motif containing 25 (TRIM25) in cancer cells to trigger TRIM25-mediated K48-linked ubiquitination of glutathione peroxidase 4 (GPX4), resulting in proteasomal degradation.

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