KT 474
Product Specifications
CAS Number
2432994-31-3
Synonyms
SAR-444656
SKU
C01784-1mg
Target
IRAK
Applications
Immunology & Inflammation
Additionnal Information
KT-474 (SAR444656) is a selective small-molecule degrader of IRAK4 in development for the treatment of TLR/IL-1R–driven autoimmune diseases. KT-474 potently downregulates R848 (TLR7/8) and lipopolysaccharide (LPS) -induced IL-6 and IL-8 production in peripheral blood mononuclear cells (PBMCs) .
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS7194268 Inquire
Rabbit anti-Escherichia coli (strain K12) HCAR Polyclonal Antibody
Sign In for Pricing
View Details 
EIA07693p 1 Kit
Porcine eosinophil-associated ribonuclease A family member 2 (EAR2) ELISA Kit
Sign In for Pricing
View Details 
EKU03308 96 Tests
Rabbit Collagen Type I Alpha 2 (COL1a2) ELISA Kit
Sign In for Pricing
View Details RYB18104-01 100 mg
2-[ (4-Methylphenyl) methyl]-1,3-thiazole-4-carboxylic acid
Sign In for Pricing
View Details RYB18104-02 1 g
2-[ (4-Methylphenyl) methyl]-1,3-thiazole-4-carboxylic acid
Sign In for Pricing
View Details