KT 474
Product Specifications
CAS Number
2432994-31-3
Synonyms
SAR-444656
SKU
C01784-1mg
Target
IRAK
Applications
Immunology & Inflammation
Additionnal Information
KT-474 (SAR444656) is a selective small-molecule degrader of IRAK4 in development for the treatment of TLR/IL-1R–driven autoimmune diseases. KT-474 potently downregulates R848 (TLR7/8) and lipopolysaccharide (LPS) -induced IL-6 and IL-8 production in peripheral blood mononuclear cells (PBMCs) .
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
TL505602V 500 µL Each
Pds5b Mouse shRNA Lentiviral Particle (Locus ID 100710)
Sign In for Pricing
View Details 
GTR15270734 1 Vial
Lentiviral mouse Znrd1as shRNA (UAS) - Lentiviral mouse Znrd1as shRNA (UAS, iRFP) (25)
Sign In for Pricing
View Details