Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Elsubrutinib

Product Specifications

CAS Number

1643570-24-4

Synonyms

ABBV-105

SKU

C01770-1mg

Target

BTK

Applications

Protein Tyrosine Kinase

Additionnal Information

Elsubrutinib (ABBV-105) is a covalent, irreversible, potent, and highly selective inhibitor of Bruton’s Tyrosine Kinase (BTK), with an IC50 of 0.18 μM for BTK catalytic domain. It specifically inhibits BTK dependent cellular functions, including both BCR and FcγR mediated signaling. It also exhibits significant efficacy in pre-clinical mechanistic models of antibody production, as well as in models of rheumatoid arthritis and lupus.

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

GRM8 Rabbit pAb (APR25044N)
APR25044N-01 50 µL

GRM8 Rabbit pAb (APR25044N)

Sign In for Pricing
View Details
GRM8 Rabbit pAb (APR25044N)
APR25044N-02 100 µL

GRM8 Rabbit pAb (APR25044N)

Sign In for Pricing
View Details
GRM8 Rabbit pAb (APR25044N)
APR25044N-03 200 µL

GRM8 Rabbit pAb (APR25044N)

Sign In for Pricing
View Details
Recombinant Human Natural resistance-associated macrophage protein 2 (SLC11A2), partial
MBS953316-01 1 mg (E-Coli)

Recombinant Human Natural resistance-associated macrophage protein 2 (SLC11A2), partial

Sign In for Pricing
View Details
Recombinant Human Natural resistance-associated macrophage protein 2 (SLC11A2), partial
MBS953316-02 1 mg (Yeast)

Recombinant Human Natural resistance-associated macrophage protein 2 (SLC11A2), partial

Sign In for Pricing
View Details
Mouse Monoclonal p53 Antibody (PAb 240) [Janelia Fluor 646]
NB200-103JF646 0.1 mL

Mouse Monoclonal p53 Antibody (PAb 240) [Janelia Fluor 646]

Sign In for Pricing
View Details