What is the catalog number for LUNA18?

The catalog number for LUNA18 is C01744.

What sizes are available for LUNA18?

LUNA18 is available in the following size(s): 1 mg.

LUNA18 is currently made to order / not held in immediate stock. Contact us for lead time.

LUNA18

Product Specifications

CAS Number

2676177-63-0

Synonyms

Paluratide

SKU

C01744-1mg

Target

Ras

Applications

Apoptosis

Additionnal Information

LUNA18 (Paluratide) is an orally bioavailable 11-mer cyclic peptide KRAS inhibitor for the intracellular tough target RAS. It binds to KRASG12D with a kd of 0.043 nM and blocks KRASG12D–SOS1 interaction at IC50 of < 2.2 nM. It also exhibits antiproliferative activity in KRAS-mutant cancer cell lines with an IC50 of 1.4 nM in AsPC-1 pancreatic cancer cells.