LUNA18
Product Specifications
CAS Number
2676177-63-0
Synonyms
Paluratide
SKU
C01744-1mg
Target
Ras
Applications
Apoptosis
Additionnal Information
LUNA18 (Paluratide) is an orally bioavailable 11-mer cyclic peptide KRAS inhibitor for the intracellular tough target RAS. It binds to KRASG12D with a kd of 0.043 nM and blocks KRASG12D–SOS1 interaction at IC50 of < 2.2 nM. It also exhibits antiproliferative activity in KRAS-mutant cancer cell lines with an IC50 of 1.4 nM in AsPC-1 pancreatic cancer cells.
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
HP200502 200 Reactions
Myelin Protein Zero (MPZ) Human qPCR Primer Pair (NM_000530)
Ask
View Details MBS1485074-01 0.02 mg (E-Coli)
Recombinant Corynebacterium jeikeium 10 kDa chaperonin (groS)
Ask
View Details MBS1485074-02 0.1 mg (E-Coli)
Recombinant Corynebacterium jeikeium 10 kDa chaperonin (groS)
Ask
View Details 
MBS1485074-03 0.02 mg (Yeast)
Recombinant Corynebacterium jeikeium 10 kDa chaperonin (groS)
Ask
View Details MBS1485074-04 0.1 mg (Yeast)
Recombinant Corynebacterium jeikeium 10 kDa chaperonin (groS)
Ask
View Details