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DB2313

Product Specifications

CAS Number

2170606-74-1

SKU

C01715-5mg

Target

Immunology & Inflammation related

Applications

Immunology & Inflammation

Additionnal Information

DB2313 is a potent inhibitor of the transcription factor PU.1, effectively blocking PU.1-dependent reporter gene transactivation with an IC50 of 5 μM. DB2313 demonstrated significant anti-leukemic activity by inducing apoptosis in acute myeloid leukemia (AML) cells. It also increases survival rates and reduces tumor burden in vivo.

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