I-138
Product Specifications
CAS Number
2098211-50-6
SKU
C01695-5mg
Target
DUB
Applications
Ubiquitin
Additionnal Information
I-138 is an orally active, potent reversible inhibitor of USP1-UAF1 with IC50 0f 4.1 nM. I-138 is structurally related to ML323 and induces the monoubiquitination of FANCD2 and PCNA in MDA-MB-436 cells and increases PCNA and FANCD2 monoubiquitination in HAP-1 USP1 WT cells.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
orb2818543 100 µg
Zebrafish ALCAMA Rabbit Polyclonal Antibody (APC)
Sign In for Pricing
View Details