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Butyrolactone 3

Product Specifications

CAS Number

778649-18-6

Synonyms

MB-3

SKU

C01652-1mg

Target

Histone Acetyltransferase

Applications

Epigenetics

Additionnal Information

Butyrolactone 3 is a non-irreversible inhibitor of the histone acetyltransferase Gcn5, with an IC50 of 100 μM. It selectively targets the Gcn5/PCAF family exhibiting weak inhibition of CBP HAT with an IC50 of 0.5 mM and also inhibits pre-mRNA splicing in vitro before catalysis, with an IC50 of 0.5 mM.

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