MLT-985
Product Specifications
UNSPSC Description
MLT-985 is a highly selective allosteric MALT1 inhibitor with an IC50 value of 3 nM.
Target Antigen
MALT1
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease;NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mlt-985.html
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CO[C@H](C1=C(NC(NC2=CN=C(N3N=CC=N3)C(Cl)=C2)=O)C=NC4=CC(Cl)=NN14)C
Molecular Weight
448.27
References & Citations
[1]Quancard J, et al. Optimization of the In Vivo Potency of Pyrazolopyrimidine MALT1 Protease Inhibitors by Reducing Metabolism and Increasing Potency in Whole Blood. J Med Chem. 2020 Dec 10;63(23):14594-14608.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-142648/MLT-985-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-142648/MLT-985-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1832576-25-6
Available Sizes
Curated Selection
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