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Tenapanor

Product Specifications

CAS Number

1234423-95-0

Synonyms

AZD1722, RDX5791

SKU

C01534-5mg

Target

Sodium Channel

Applications

Transmembrane Transporters

Additionnal Information

Tenapanor (AZD1722, RDX5791) is a potent and orally active inhibitor of sodium/hydrogen exchanger isoform 3 (NHE3) . It exhibits an IC50 of 2 and 6 nM in human and mouse ileum monolayers, respectively. Tenapanor reduces intestinal phosphate absorption predominantly by reducing passive paracellular phosphate flux.

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